Surface-Controlled Mono/Diselective ortho C-H Bond Activation.

One of the most charming and challenging topics in organic chemistry is the selective C-H bond activation. The difficulty arises not only from the relatively large bond-dissociation enthalpy, but also from the poor reaction selectivity. In this work, Au(111) and Ag(111) surfaces were used to address...

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Publicado en:Journal of the American Chemical Society Vol. 138; no. 8; pp. 2809 - 2815
Autores principales: Qing Li, Biao Yang, Haiping Lin, Nabi Aghdassi, Kangjian Miao, Junjie Zhang, Haiming Zhang, Youyong Li, Steffen Duhm, Jian Fan, Lifeng Chi
Formato: Artículo
Publicado: American Chemical Society 3/2/2016
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Acceso en línea:Ver este registro en EBSCOhost
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        10.1021/jacs.5b13286
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        atl: Surface-Controlled Mono/Diselective ortho C-H Bond Activation.
      aug:
        au:
          Qing Li
          Biao Yang
          Haiping Lin
          Nabi Aghdassi
          Kangjian Miao
          Junjie Zhang
          Haiming Zhang
          Youyong Li
          Steffen Duhm
          Jian Fan
          Lifeng Chi
        affil: Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu P. R. China
      su:
        Carbon-hydrogen bonds
        Dehydrogenation kinetics
        Density functional theory
        Organic synthesis
        Oxidation of phenol
      sug:
        subj:
          Carbon-hydrogen bonds
          Dehydrogenation kinetics
          Density functional theory
          Organic synthesis
          Oxidation of phenol
      ab: One of the most charming and challenging topics in organic chemistry is the selective C-H bond activation. The difficulty arises not only from the relatively large bond-dissociation enthalpy, but also from the poor reaction selectivity. In this work, Au(111) and Ag(111) surfaces were used to address ortho C-H functionalization and ortho-ortho couplings of phenol derivatives. More importantly, the competition between dehydrogenation and deoxygenation drove the diversity of reaction pathways of phenols on surfaces, that is, diselective ortho C-H bond activation on Au(111) surfaces and monoselective ortho C-H bond activation on Ag(111) surfaces. The mechanism of this unprecedented phenomenon was extensively explored by scanning tunneling microscopy, density function theory, and X-ray photoelectron spectroscopy. Our findings provide new pathways for surface-assisted organic synthesis via the mono/diselective C-H bond activation.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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