Gender-Related Lymphocyte Subjects Comparison in Epileptic and Healthy Subjects.
Objective: This study was conducted to compare the lymphocyte subsets in gender-related epileptic patients and healthy subjects. Study Design: Comparative cross-sectional study Materials and Methods: A comparative cross-sectional study was conducted involving a total of 190 subjects with 95 of them...
| Publicado en: | International Medical Journal Vol. 23; no. 2; pp. 166 - 169 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Japan International Cultural Exchange Foundation
Apr2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=114899011&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 114899011 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13412051 23J1 jtl: International Medical Journal issn: 13412051 maglogo: N pubinfo: dt: Apr2016 vid: 23 iid: 2 pid: 29386 pub: Japan International Cultural Exchange Foundation artinfo: ui: 114899011 114899011 114899011 114899011 ppf: 166 ppct: 3 formats: fmt: @attributes: type: P tig: atl: Gender-Related Lymphocyte Subjects Comparison in Epileptic and Healthy Subjects. aug: au: Wan Zuraida WAH Siti Nurul 'Ashikin S Mustaffa M Shalini John Tarakan K affil: Department of Immunology, Universiti Sains Malaysia, Health Campus 16150 Kubang Kerian, Kelantan, Malaysia sug: subj: Epilepsy Lymphocyte Subsets Human Cross Sectional Studies Male Female Sex Factors T-Tests Data Analysis Software Confidence Intervals P-Value Flow Cytometry Male Female ab: Objective: This study was conducted to compare the lymphocyte subsets in gender-related epileptic patients and healthy subjects. Study Design: Comparative cross-sectional study Materials and Methods: A comparative cross-sectional study was conducted involving a total of 190 subjects with 95 of them were epileptic and the remaining 95 subjects were healthy subjects. Peripheral blood samples were processed and analyzed to determine the lymphocyte subsets (CD3+, CD4+, CD8+, CDI9+ and CD16+56+) via flow cytometric analysis (FACS Canto, Becton-Dickinson). Data was analyzed by Independent T-test using SPSS programme version 12.0. Results: Results demonstrated that there were significant difference between healthy and epileptic male in almost all lymphocyte subsets studied but no significant difference found in female subjects. Statistically significant differences included the increment of CD3+ (95% CI: 0.08, 0.36; p value = 0.002), CD4+ (95% CI : 0.02, 0.21; p value = 0.018), CD19+ (95% CI : 0.03, 0.14; p value = 0.002) and CD8+ (95% CI : 0.001, 0.17; p value = 0.048). Whereas, no significant difference found in CD16+56+. Conclusion: A significant increased in lymphocyte subsets counts may suggest that there were cellular immune derangements in male epileptic patients. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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