Brief Report: The Prevalence of Neurofibromatosis Type 1 among Children with Autism Spectrum Disorder Identified by the Autism and Developmental Disabilities Monitoring Network.
Neurofibromatosis type 1 (NF1) is an inherited neurocutaneous disorder associated with neurodevelopmental disorders including autism spectrum disorder (ASD). The frequency of ASD/NF1 co-occurrence has been subject to debate since the 1980s. This relationship was investigated in a large population-ba...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 46; no. 10; pp. 3369 - 3377 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=118414138&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 118414138 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Oct2016 vid: 46 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 118414138 118414138 118414138 10.1007/s10803-016-2877-3 118414138 ppf: 3369 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Brief Report: The Prevalence of Neurofibromatosis Type 1 among Children with Autism Spectrum Disorder Identified by the Autism and Developmental Disabilities Monitoring Network. aug: au: Bilder, Deborah Bakian, Amanda Stevenson, David Carbone, Paul Cunniff, Christopher Goodman, Alyson McMahon, William Fisher, Nicole Viskochil, David affil: Utah Autism Research Program, Department of Psychiatry , University of Utah , 650 Komas Drive, Suite 206 Salt Lake City 84108 USA sug: subj: Neurofibromatosis 1 Epidemiology Autism Spectrum Disorder Developmental Disabilities Nonverbal Communication Human Child DSM Coding Comparative Studies Comorbidity Regression Goodness of Fit Chi Square Test T-Tests Variable Data Analysis Software Confidence Intervals P-Value Sensitivity and Specificity Funding Source Germany Child: 6-12 years ab: Neurofibromatosis type 1 (NF1) is an inherited neurocutaneous disorder associated with neurodevelopmental disorders including autism spectrum disorder (ASD). The frequency of ASD/NF1 co-occurrence has been subject to debate since the 1980s. This relationship was investigated in a large population-based sample of 8-year-old children identified with ASD (N = 12,271) by the Centers for Disease Control and Prevention's Autism and Developmental Disabilities Monitoring (ADDM) Network. Twenty-two (1-in-558) children with ASD had diagnosed NF1, exceeding NF1 general population estimates by four to five fold. Children with ASD/NF1 versus ASD without NF1 were significantly less likely to receive a community-based ASD diagnosis ( p = 0.04) and understand non-verbal communication ( p = 0.001). These findings underscore the importance of including social-communication ability among relevant developmental concerns in children with NF1. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Unknown language: English refInfo: holdings: @attributes: islocal: N |
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