The impact of protein quality on the promotion of resistance exercise-induced changes in muscle mass.

Protein supplementation during resistance exercise training augments hypertrophic gains. Protein ingestion and the resultant hyperaminoacidemia provides the building blocks (indispensable amino acids - IAA) for, and also triggers an increase in, muscle protein synthesis (MPS), suppression of muscle...

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Publicado en:Nutrition & Metabolism Vol. 13; pp. 1 - 10
Autor principal: Phillips, Stuart M.
Formato: review tables/charts Journal Article
Publicado: BioMed Central 9/29/2016
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Nutrition & Metabolism
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      dt: 9/29/2016
      vid: 13
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      pub: BioMed Central
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        10.1186/s12986-016-0124-8
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        atl: The impact of protein quality on the promotion of resistance exercise-induced changes in muscle mass.
      aug:
        au: Phillips, Stuart M.
        affil: Department of Kinesiology, McMaster University, 1280 Main St., West Hamilton, ON L8S 4K1, Canada
      sug:
        subj:
          Resistance Training
          Muscle Strengthening
          Hypertrophy
          Dietary Proteins Metabolism
          Dietary Supplements Standards
          Leucine Standards
          Dietary Proteins Standards
          Dietary Proteins Classification
          Amino Acids
      ab: Protein supplementation during resistance exercise training augments hypertrophic gains. Protein ingestion and the resultant hyperaminoacidemia provides the building blocks (indispensable amino acids - IAA) for, and also triggers an increase in, muscle protein synthesis (MPS), suppression of muscle protein breakdown (MPB), and net positive protein balance (i.e., MPS > MPB). The key amino acid triggering the rise in MPS is leucine, which stimulates the mechanistic target of rapamycin complex-1, a key signalling protein, and triggers a rise in MPS. As such, ingested proteins with a high leucine content would be advantageous in triggering a rise in MPS. Thus, protein quality (reflected in IAA content and protein digestibility) has an impact on changes in MPS and could ultimately affect skeletal muscle mass. Protein quality has been measured by the protein digestibility-corrected amino acid score (PDCAAS); however, the digestible indispensable amino acid score (DIAAS) has been recommended as a better method for protein quality scoring. Under DIAAS there is the recognition that amino acids are individual nutrients and that protein quality is contingent on IAA content and ileal (as opposed to fecal) digestibility. Differences in protein quality may have important ramifications for exercise-induced changes in muscle mass gains made with resistance exercise as well as muscle remodelling. Thus, the purpose of this review is a critical appraisal of studies examining the effects of protein quality in supplementation on changes in muscle mass and strength as well as body composition during resistance training.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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