Effect of Sulindac Binary System on In Vitro and In Vivo Release Profiles: An Assessment of Polymer Type and Its Ratio.

The bioavailability of sulindac (SDC), a nonsteroidal anti-inflammatory drug, is low due to poor aqueous solubility and poor dissolution rate. For this reason it is necessary to enhance the solubility and enhance dissolution of the drug by dispersing SDC in polyethylene glycols 6000 (PEG 6000) and p...

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Publicado en:BioMed Research International Vol. 2016; pp. 1 - 10
Autor principal: Shazly, Gamal A.
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 10/20/2016
Acceso en línea:Ver este registro en EBSCOhost