Latent herpes simplex virus in human trigeminal ganglia. Detection of an immediate early gene "anti-sense" transcript by in situ hybridization.

We used in situ hybridization to study the expression of herpes simplex virus type 1 genes during latent infections of human sensory ganglia. Trigeminal ganglia were recovered at autopsy from 24 subjects with no evidence of an active herpetic infection. These ganglia were hybridized to 35S-labeled s...

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Bibliographic Details
Published in:New England Journal of Medicine Vol. 317; no. 23; pp. 1427 - 1433
Main Authors: Croen, K D, Ostrove, J M, Dragovic, L J, Smialek, J E, Straus, S E
Format: research Journal Article
Published: New England Journal of Medicine 12/3/87
Online Access:View this record in EBSCOhost