Bi-phasic regulation of glycogen content in astrocytes via Cav-1/PTEN/PI3K/AKT/GSK-3β pathway by fluoxetine.

Objective: Here, we present the data indicating that chronic treatment with fluoxetine regulates Cav-1/PTEN/PI3K/AKT/GSK-3β signalling pathway and glycogen content in primary cultures of astrocytes with bi-phasic concentration dependence. Results: At lower concentrations, fluoxetine downregulates ge...

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Detalles Bibliográficos
Publicado en:Psychopharmacology Vol. 234; no. 7; pp. 1069 - 1078
Autores principales: Bai, Qiufang, Song, Dan, Gu, Li, Verkhratsky, Alexei, Peng, Liang
Formato: Journal Article
Publicado: Springer Nature Apr2017
Acceso en línea:Ver este registro en EBSCOhost