RANKL coordinates multiple osteoclastogenic pathways by regulating expression of ubiquitin ligase RNF146.

Bone undergoes continuous remodeling due to balanced bone formation and resorption mediated by osteoblasts and osteoclasts, respectively. Osteoclasts arise from the macrophage lineage, and their differentiation is dependent on RANKL, a member of the TNF family of cytokines. Here, we have provided ev...

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Bibliographic Details

Published in:	Journal of Clinical Investigation Vol. 127; no. 4; pp. 1303 - 1316
Main Authors:	Yoshinori Matsumoto, Larose, Jose, Kent, Oliver A., Lim, Melissa, Changoor, Adele, Zhang, Lucia, Storozhuk, Yaryna, Xiaohong Mao, Grynpas, Marc D., Feng Cong, Rottapel, Robert, Matsumoto, Yoshinori, Mao, Xiaohong, Cong, Feng
Format:	Journal Article
Published:	American Society for Clinical Investigation 4/3/2017
Online Access:	View this record in EBSCOhost