Intradomain Allosteric Network Modulates Calcium Affinity of the C-Type Lectin Receptor Langerin.

Antigen uptake and processing by innate immune cells is crucial to initiate the immune response. Therein, the endocytic C-type lectin receptors serve as pattern recognition receptors, detecting pathogens by their glycan structures. Herein, we studied the carbohydrate recognition domain of Langerin,...

Descripción completa

Detalles Bibliográficos

Publicado en:	Journal of the American Chemical Society Vol. 139; no. 37; pp. 12176 - 12187
Autores principales:	Hanske, Jonas, Shanina, Elena, Rademacher, Christoph, Aleksic, Stevan, Keller, Bettina G., Ballaschk, Martin, Beerbaum, Monika, Schmieder, Peter, Jurk, Marcel
Formato:	Artículo
Publicado:	American Chemical Society 9/21/2017
Materias:	Antigens Immune response Pattern perception Pathogenic microorganisms Diagnostic microbiology Glycan structure
Acceso en línea:	Ver este registro en EBSCOhost