Rationalization of Anomalous Pseudocontact Shifts and Their Solvent Dependence in a Series of C-Symmetric Lanthanide Complexes.

Bleaney's long-standing theory of magnetic anisotropy has been employed with some success for many decades to explain paramagnetic NMR pseudocontact shifts, and has been the subject of many subsequent approximations. Here, we present a detailed experimental and theoretical investigation accounting f...

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Publicado en:Journal of the American Chemical Society Vol. 139; no. 40; pp. 14166 - 14173
Autores principales: Vonci, Michele, Mason, Kevin, Suturina, Elizaveta A., Frawley, Andrew T., Worswick, Steven G., Kuprov, Ilya, Parker, David, McInnes, Eric J. L., Chilton, Nicholas F.
Formato: Artículo
Publicado: American Chemical Society 10/11/2017
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: Rationalization of Anomalous Pseudocontact Shifts and Their Solvent Dependence in a Series of C-Symmetric Lanthanide Complexes.
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          Vonci, Michele
          Mason, Kevin
          Suturina, Elizaveta A.
          Frawley, Andrew T.
          Worswick, Steven G.
          Kuprov, Ilya
          Parker, David
          McInnes, Eric J. L.
          Chilton, Nicholas F.
        affil:
          School of Chemistry, The University of Manchester, Oxford Road, Manchester M13 9PL, U.K.
          Department of Chemistry, Durham University, South Road, Durham DH1 3LE, U.K
          School of Chemistry, The University of Southampton, Highfield, Southampton SO17 1BJ, U.K.
      su:
        Magnetic anisotropy
        Rare earth metals
        Magnetic susceptibility
        Magnetic resonance
        Triazacyclononane
        Electronic structure
      sug:
        subj:
          Magnetic anisotropy
          Rare earth metals
          Magnetic susceptibility
          Magnetic resonance
          Triazacyclononane
          Electronic structure
      ab: Bleaney's long-standing theory of magnetic anisotropy has been employed with some success for many decades to explain paramagnetic NMR pseudocontact shifts, and has been the subject of many subsequent approximations. Here, we present a detailed experimental and theoretical investigation accounting for the anomalous solvent dependence of NMR shifts for a series of lanthanide(III) complexes, namely [LnL¹] (Ln = Eu, Tb, Dy, Ho, Er, Tm, and Yb; L¹: 1,4,7-tris[(6-carboxypyridin-2-yl)methyl]-1,4,7-triazacyclononane), taking into account the effect of subtle ligand flexibility on the electronic structure. We show that the anisotropy of the room temperature magnetic susceptibility tensor, which in turn affects the sign and magnitude of the pseudocontact chemical shift, is extremely sensitive to minimal structural changes in the first coordination sphere of L¹. We show that DFT structural optimizations do not give accurate structural models, as assessed by the experimental chemical shifts, and thus we determine a magnetostructural correlation and employ this to evaluate the accurate solution structure for each [LnL¹]. This approach allows us to explain the counterintuitive pseudocontact shift behavior, as well as a striking solvent dependence. These results have important consequences for the analysis and design of novel magnetic resonance shift and optical emission probes that are sensitive to the local solution environment and polarity.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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          year: 2017
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