The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells.

Background. We aimed to investigate the effect and mechanism of curcumin (CUR) in Alzheimer’s disease (AD). Methods. Mouse hippocampal neuronal cell line HT-22 was treated with Aβ1–42 and/or CUR, and then cell viability was evaluated by cell counting kit 8, Beclin-l level was detected using western...

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Bibliographic Details
Published in:BioMed Research International Vol. 2018; pp. 1 - 9
Main Authors: Zhang, Lu, Fang, Yu, Cheng, Xuan, Lian, Yajun, Zeng, Zhaoshu, Wu, Chuanjie, Zhu, Hongcan, Xu, Hongliang
Format: diagnostic images research tables/charts Journal Article
Published: Wiley-Blackwell 1/15/2018
Online Access:View this record in EBSCOhost