Highly variable absorption of clavulanic acid during the day: a population pharmacokinetic analysis.
Objectives: To calculate the clavulanic acid exposure of oral amoxicillin/clavulanic acid dosing regimens, to investigate variability using a population pharmacokinetic model and to explore target attainment using Monte Carlo simulations.Methods: Two groups of healthy male volunteers received amoxic...
| Publicado en: | Journal of Antimicrobial Chemotherapy (JAC) Vol. 73; no. 2; pp. 469 - 477 |
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| Autores principales: | , , , , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
Feb2018
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| Acceso en línea: | Ver este registro en EBSCOhost |