Tomentodione E, a new sec-pentyl syncarpic acid-based meroterpenoid from the leaves of Rhodomyrtus tomentosa.
A new meroterpenoid, tomentodione E (1), along with four known ones (2-5) were isolated from the leaves of Rhodomyrtus tomentosa. Their structures were elucidated based on extensive spectroscopic data as well as computational methods. Compound 1 represents the first example of meroterpenoid possessi...
| Publicado en: | Journal of Asian Natural Products Research Vol. 20; no. 1; pp. 67 - 75 |
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| Autores principales: | , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jan2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=127591361&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 127591361 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10286020 J40 jtl: Journal of Asian Natural Products Research issn: 10286020 maglogo: Y pubinfo: dt: Jan2018 vid: 20 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 127591361 127591361 127591361 10.1080/10286020.2017.1318852 127591361 ppf: 67 ppct: 8 formats: tig: atl: Tomentodione E, a new sec-pentyl syncarpic acid-based meroterpenoid from the leaves of Rhodomyrtus tomentosa. aug: au: Liu, Jie Song, Jian-Guo Su, Jun-Cheng Huang, Xiao-Jun Ye, Wen-Cai Wang, Ying affil: Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou510632, China sug: subj: Terpenes Analysis Terpenes Administration and Dosage Plant Leaves Analysis Molecular Structure In Vitro Studies Respiratory Syncytial Viruses Drug Effects Respiratory Syncytial Virus Infections Drug Therapy Biological Assay Mass Spectrometry Magnetic Resonance Spectroscopy Ribavirin Administration and Dosage Funding Source ab: A new meroterpenoid, tomentodione E (1), along with four known ones (2-5) were isolated from the leaves of Rhodomyrtus tomentosa. Their structures were elucidated based on extensive spectroscopic data as well as computational methods. Compound 1 represents the first example of meroterpenoid possessing a sec-pentyl syncarpic acid motif coupled with a caryophyllene. Compounds 1-4 were evaluated for their in vitro antiviral activity against respiratory syncytial virus (RSV) with cytopathic effect (CPE) reduction assay, and 2 showed potent in vitro anti-RSV effect. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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