Pharmacokinetics of CYP2C9, CYP2C19, and CYP2D6 substrates in healthy Chinese and European subjects.

Purpose: The aim of this analysis is to compare the pharmacokinetics of drug substrates in healthy Chinese and European subjects of aligned CYP2C9, CYP2C19, or CYP2D6 enzyme activity, providing further insight into drivers of interethnic differences in pharmacokinetics.Methods: Following identificat...

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Bibliographic Details
Published in:European Journal of Clinical Pharmacology Vol. 74; no. 3; pp. 285 - 297
Main Authors: Lu, Sijie, Nand, R. A., Yang, J. S., Chen, Gang, Gross, A. S.
Format: research systematic review tables/charts Journal Article
Published: Springer Nature Mar2018
Online Access:View this record in EBSCOhost