CYP2C19 genotype has a major influence on labetalol pharmacokinetics in healthy male Chinese subjects.
Purpose: The pharmacokinetics (PK) of labetalol show wide inter-subject variability, but the genetic causes for this are largely undetermined. This study was performed to examine whether common polymorphisms in UGT1A1, UGT2B7, CYP2C19 and ABCB1 affect the PK of labetalol. Methods: The PK of labetalo...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 69; no. 4; pp. 799 - 807 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Apr2013
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| Acceso en línea: | Ver este registro en EBSCOhost |