miRNA 146a promotes chemotherapy resistance in lung cancer cells by targeting DNA damage inducible transcript 3 (CHOP).
The underlying molecular mechanism of lung cancer drug resistance is poorly understood. The mediator of endoplasmic reticulum stress CHOP (DNA damage inducible transcript 3) promotes stress-induced apoptosis and appears to function as a transcription factor in multiple diseases. However, its potenti...
| Published in: | Cancer Letters Vol. 428; pp. 55 - 69 |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | research Journal Article |
| Published: |
Elsevier B.V.
Aug2018
|
| Online Access: | View this record in EBSCOhost |