miRNA 146a promotes chemotherapy resistance in lung cancer cells by targeting DNA damage inducible transcript 3 (CHOP).

The underlying molecular mechanism of lung cancer drug resistance is poorly understood. The mediator of endoplasmic reticulum stress CHOP (DNA damage inducible transcript 3) promotes stress-induced apoptosis and appears to function as a transcription factor in multiple diseases. However, its potenti...

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Bibliographic Details
Published in:Cancer Letters Vol. 428; pp. 55 - 69
Main Authors: Tan, Wenfeng, Liao, Yi, Qiu, Yang, Liu, Hongxiang, Tan, Deli, Wu, Tao, Tang, Meng, Zhang, Shixin, Wang, Haidong
Format: research Journal Article
Published: Elsevier B.V. Aug2018
Online Access:View this record in EBSCOhost