LIMK/cofilin pathway and Slingshot are implicated in human colorectal cancer progression and chemoresistance.
Cofilin phospho-regulation is important for actin filament turnover and is implicated in cancer. Phosphorylation of cofilin is mediated by LIM kinases (LIMKs) and dephosphorylation by Slingshot phosphatases (SSH). LIMKs and SSH promote cancer cell invasion and metastasis and represent novel anti-can...
| Publicado en: | Virchows Archiv: European Journal of Pathology Vol. 472; no. 5; pp. 727 - 738 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
May2018
|
| Acceso en línea: | Ver este registro en EBSCOhost |