Dynamics and Thermodynamics of Transthyretin Association from Molecular Dynamics Simulations.
Molecular dynamics simulations are used in this work to probe the structural stability and the dynamics of engineered mutants of transthyretin (TTR), i.e., the double mutant F87M/L110M (MT-TTR) and the triple mutant F87M/L110M/S117E (3M-TTR), in relation to wild-type. Free energy analysis from end-p...
| Publicado en: | BioMed Research International Vol. 2018; pp. 1 - 15 |
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| Autores principales: | , , , , |
| Formato: | equations & formulas pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
6/5/2018
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| Acceso en línea: | Ver este registro en EBSCOhost |