Wee1 Inhibitor AZD1775 Combined with Cisplatin Potentiates Anticancer Activity against Gastric Cancer by Increasing DNA Damage and Cell Apoptosis.

Based on the mechanisms by which Wee1 inhibitor and cisplatin played their own role, a promising strategy of Wee1 inhibitor combined with cisplatin was proposed, which was investigated in gastric cancer (GC). Either Wee1 inhibitor AZD1775 or cisplatin alone had a certain inhibitory effect on in vitr...

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Detalles Bibliográficos
Publicado en:BioMed Research International Vol. 2018; pp. 1 - 11
Autores principales: Chen, Dongshao, Lin, Xiaoting, Gao, Jing, Shen, Lin, Li, Zhongwu, Dong, Bin, Zhang, Cheng, Zhang, Xiaotian
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 6/7/2018
Acceso en línea:Ver este registro en EBSCOhost