Wee1 Inhibitor AZD1775 Combined with Cisplatin Potentiates Anticancer Activity against Gastric Cancer by Increasing DNA Damage and Cell Apoptosis.

Based on the mechanisms by which Wee1 inhibitor and cisplatin played their own role, a promising strategy of Wee1 inhibitor combined with cisplatin was proposed, which was investigated in gastric cancer (GC). Either Wee1 inhibitor AZD1775 or cisplatin alone had a certain inhibitory effect on in vitr...

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Bibliographic Details

Published in:	BioMed Research International Vol. 2018; pp. 1 - 11
Main Authors:	Chen, Dongshao, Lin, Xiaoting, Gao, Jing, Shen, Lin, Li, Zhongwu, Dong, Bin, Zhang, Cheng, Zhang, Xiaotian
Format:	pictorial research tables/charts Journal Article
Published:	Wiley-Blackwell 6/7/2018
Online Access:	View this record in EBSCOhost