Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women.

Background: Ample evidence implicates cellular senescence as a contributor to frailty and functional decline in rodents, but considerable effort remains to translate these findings to human aging.Methods: We quantified senescence biomarker p16INK4a-expressing cells in thigh adipose tissue obtained f...

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Detalles Bibliográficos
Publicado en:Journals of Gerontology Series A: Biological Sciences & Medical Sciences Vol. 73; no. 7; pp. 939 - 946
Autores principales: Justice, Jamie N., Gregory, Heather, Tchkonia, Tamar, LeBrasseur, Nathan K., Kirkland, James L., Kritchevsky, Stephen B., Nicklas, Barbara J.
Formato: research Journal Article
Publicado: Oxford University Press / USA Jul2018
Acceso en línea:Ver este registro en EBSCOhost