Systematic approach for the formulation and optimization of atorvastatin loaded solid lipid NANOAPARTICLES using response surface methodology.

Atorvastatin is a lipid lowering agent with poor oral bioavailability (12%) because of poor solubility and extensive first pass hepatic metabolism. In order to overcome these issues, atorvastatin loaded solid lipid nanoparticles (ATOR-SLNs) were prepared by using glyceryl tripalmitate as lipid carri...

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Bibliographic Details
Published in:Biomedical Microdevices Vol. 20; no. 3; pp. 1 - 2
Main Authors: Sarangi, Babita, Jana, Utpal, Sahoo, Jyotirmaya, Mohanta, Guru Prasad, Manna, Prabal Kumar
Format: Journal Article
Published: Springer Nature Sep2018
Online Access:View this record in EBSCOhost