Systematic approach for the formulation and optimization of atorvastatin loaded solid lipid NANOAPARTICLES using response surface methodology.

Atorvastatin is a lipid lowering agent with poor oral bioavailability (12%) because of poor solubility and extensive first pass hepatic metabolism. In order to overcome these issues, atorvastatin loaded solid lipid nanoparticles (ATOR-SLNs) were prepared by using glyceryl tripalmitate as lipid carri...

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Detalles Bibliográficos
Publicado en:Biomedical Microdevices Vol. 20; no. 3; pp. 1 - 2
Autores principales: Sarangi, Babita, Jana, Utpal, Sahoo, Jyotirmaya, Mohanta, Guru Prasad, Manna, Prabal Kumar
Formato: Journal Article
Publicado: Springer Nature Sep2018
Acceso en línea:Ver este registro en EBSCOhost