Preliminary findings of altered functional connectivity of the default mode network linked to functional outcomes one year after pediatric traumatic brain injury.
Purpose and Method: This study examined functional connectivity of the default mode network (DMN) and examined brain-behavior relationships in a pilot cohort of children with chronic mild to moderate traumatic brain injury (TBI). Results: Compared to uninjured peers, children with TBI demonstrated l...
| Publicado en: | Developmental Neurorehabilitation Vol. 21; no. 7; pp. 423 - 431 |
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| Autores principales: | , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131350677&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131350677 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17518423 2Y75 jtl: Developmental Neurorehabilitation issn: 17518423 maglogo: Y pubinfo: dt: Oct2018 vid: 21 iid: 7 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 131350677 131350677 131350677 10.1080/17518423.2017.1338777 131350677 ppf: 423 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Preliminary findings of altered functional connectivity of the default mode network linked to functional outcomes one year after pediatric traumatic brain injury. aug: au: Stephens, Jaclyn A. Salorio, Cynthia F. Barber, Anita D. Risen, Sarah R. Mostofsky, Stewart H. Suskauer, Stacy J. affil: Kennedy Krieger Institute, Johns Hopkins School of Medicine, Baltimore, MD, USA sug: subj: Brain Injuries Diagnosis Neural Pathways Pathology Human Pilot Studies Prospective Studies Child Peer Group Chronic Disease Psychomotor Performance Parietal Lobe Pathology Child: 6-12 years ab: Purpose and Method: This study examined functional connectivity of the default mode network (DMN) and examined brain-behavior relationships in a pilot cohort of children with chronic mild to moderate traumatic brain injury (TBI). Results: Compared to uninjured peers, children with TBI demonstrated less anti-correlated functional connectivity between DMN and right Brodmann Area 40 (BA 40). In children with TBI, more anomalous less anti-correlated) connectivity between DMN and right BA 40 was linked to poorer performance on response inhibition tasks. Conclusion: Collectively, these preliminary findings suggest that functional connectivity between DMN and BA 40 may relate to longterm functional outcomes in chronic pediatric TBI. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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