Evaluation of Pancreatic VMAT2 Binding with Active and Inactive Enantiomers of [18F]FP-DTBZ in Healthy Subjects and Patients with Type 1 Diabetes.

Purpose: Previous studies demonstrated the utility of [18F]fluoropropyl-(+)-dihydrotetrabenazine ([18F]FP-(+)-DTBZ) as a positron emission tomography (PET) radiotracer for the vesicular monoamine transporter type 2 (VMAT2) to quantify beta cell mass in healthy control (HC) and type 1 diabetes mellit...

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Bibliographic Details
Published in:Molecular Imaging & Biology Vol. 20; no. 5; pp. 835 - 846
Main Authors: Naganawa, Mika, Lim, Keunpoong, Nabulsi, Nabeel B., Lin, Shu-fei, Labaree, David, Ropchan, Jim, Herold, Kevan C., Huang, Yiyun, Harris, Paul, Ichise, Masanori, Cline, Gary W., Carson, Richard E.
Format: research Journal Article
Published: Springer Nature Oct2018
Online Access:View this record in EBSCOhost