Myocardial multilayer strain does not provide additional value for detection of myocardial viability assessed by SPECT imaging over and beyond standard strain.

Background: The aim of this study was to evaluate the value of multilayer strain analysis to the assessment of myocardial viability (MV) through the comparison of both speckle tracking echocardiography and single‐photon emission computed tomography (SPECT) imaging. We also intended to determine whic...

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Publicado en:Echocardiography Vol. 35; no. 9; pp. 1300 - 1310
Autores principales: Orloff, Elisabeth, Fournier, Pauline, Bouisset, Frédéric, Moine, Thomas, Cournot, Maxime, Elbaz, Meyer, Carrié, Didier, Galinier, Michel, Lairez, Olivier, Cognet, Thomas
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Sep2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2018
      vid: 35
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.14022
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        atl: Myocardial multilayer strain does not provide additional value for detection of myocardial viability assessed by SPECT imaging over and beyond standard strain.
      aug:
        au:
          Orloff, Elisabeth
          Fournier, Pauline
          Bouisset, Frédéric
          Moine, Thomas
          Cournot, Maxime
          Elbaz, Meyer
          Carrié, Didier
          Galinier, Michel
          Lairez, Olivier
          Cognet, Thomas
        affil: Department of Cardiology, Rangueil University Hospital, Toulouse, France
      sug:
        subj:
          Myocardium Physiology
          Myocardium Anatomy and Histology
          Spectrophotometry
          Tomography, Emission-Computed, Single-Photon
          Human
          Cardiac Patients
          Middle Age
          Aged
          Coronary Angiography
          Diagnostic Imaging
          Middle Aged: 45-64 years
          Aged: 65+ years
      ab: Background: The aim of this study was to evaluate the value of multilayer strain analysis to the assessment of myocardial viability (MV) through the comparison of both speckle tracking echocardiography and single‐photon emission computed tomography (SPECT) imaging. We also intended to determine which segmental longitudinal strain (LS) cutoff value would be optimal to discriminate viable myocardium. Methods: We included 47 patients (average age: 61 ± 11 years) referred to our cardiac imaging center for MV evaluation. All patients underwent transthoracic echocardiography with measures of LS, SPECT, and coronary angiography. Results: In all, 799 segments were analyzed. We correlated myocardial tracer uptake by SPECT with sub‐endocardial, sub‐epicardial, and mid‐segmental LS values with r = .514 P < .0001, r = .501 P < .0001, and r = .520 P < .0001, respectively. The measurements of each layer strain (sub‐endocardial, sub‐epicardial, and mid) had the same performance to predict MV viability as defined by SPECT with areas under curve of 0.819 [0.778–0.861, P < .0001], 0.809 [0.764–0.854, P < .0001], and 0.817 [0.773–0.860, P < .0001], respectively. The receiver‐operating characteristic analysis yielded a cutoff value of −6.5% for mid‐segmental LS with a sensitivity of 76% and specificity of 76% to predict segmental MV as defined by SPECT. Conclusions: Multilayer strain analysis does not evaluate MV with more accuracy than standard segmental LS analysis.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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