The impact of underlying disease state on outcomes in patients with pyoderma gangrenosum: A national survey.
Background: Whether the underlying disease affects the outcomes in pyoderma gangrenosum (PG) is unclear.Objectives: To determine the impact of comorbid disease associations and concomitant procedural treatments on patient outcomes in hospitalizations of patients with PG.Methods: A cross-sectional an...
| Publicado en: | Journal of the American Academy of Dermatology Vol. 79; no. 4; pp. 659 - 660 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Elsevier B.V.
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131816138&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131816138 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01909622 1ZF jtl: Journal of the American Academy of Dermatology issn: 01909622 maglogo: N pubinfo: dt: Oct2018 vid: 79 iid: 4 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 131816138 131816138 NLM29438762 131816138 10.1016/j.jaad.2018.02.007 NLM29438762 131816138 ppf: 659 ppct: 1 formats: tig: atl: The impact of underlying disease state on outcomes in patients with pyoderma gangrenosum: A national survey. aug: au: Kaffenberger, Benjamin H. Hinton, Alice Krishna, Somashekar G. affil: Department of Internal Medicine, Division of Dermatology, The Ohio State University Wexner Medical Center, Columbus, Ohio sug: subj: Inflammatory Bowel Diseases Epidemiology Vasculitis Epidemiology Pyoderma Gangrenosum Epidemiology Cause of Death Hospital Mortality Arthritis, Rheumatoid Diagnosis Pyoderma Gangrenosum Therapy Arthritis, Rheumatoid Epidemiology Survival Analysis Female Cross Sectional Studies Hematologic Neoplasms Diagnosis Ohio Pyoderma Gangrenosum Diagnosis Resource Databases Risk Assessment Logistic Regression Severity of Illness Indices Retrospective Design Hospitalization Statistics and Numerical Data Inflammatory Bowel Diseases Diagnosis Prognosis Vasculitis Diagnosis Linear Regression Multivariate Analysis Hematologic Neoplasms Epidemiology Comorbidity Treatment Outcomes Male Funding Source Female Male ab: Background: Whether the underlying disease affects the outcomes in pyoderma gangrenosum (PG) is unclear.Objectives: To determine the impact of comorbid disease associations and concomitant procedural treatments on patient outcomes in hospitalizations of patients with PG.Methods: A cross-sectional analysis of the National Inpatient Sample for hospitalizations of patients with PG from the years 2002 to 2011, analyzing in-hospital mortality rate and health care resource utilization.Results: Inflammatory bowel disease was the most frequent comorbid association, followed by inflammatory arthritis, hematologic malignancies/dyscrasia, and vasculitis. Multivariable modeling showed that vasculitis and hematologic malignancy/dyscrasia, when compared with inflammatory bowel disease, were associated with a 4-fold to 6-fold increased risk of in-hospital mortality and increasing health care resource utilization. Inpatient procedural interventions, including skin grafts, biopsies, and debridement, did not affect mortality and were associated with an increased length of stay.Limitations: The database does not account for outpatient follow-up; additionally, there was a low rate of coded comorbid conditions.Conclusions: Comprehensive evaluation to determine the underlying comorbidity for patients with PG is important for patient risk stratification. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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