Dietary total antioxidant capacity and incidence of chronic kidney disease in subjects with dysglycemia: Tehran Lipid and Glucose Study.
Purpose: We aimed to investigate the association of dietary total antioxidant capacity (TAC) with incidence of CKD in subjects with dysglycemia.Methods: We followed-up 1179 subjects aged ≥30 years with dysglycemia from the Tehran Lipid and Glucose Study (TLGS) for 3 years, who were initially free of...
| Publicado en: | European Journal of Nutrition Vol. 57; no. 7; pp. 2377 - 2386 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131975642&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131975642 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Oct2018 vid: 57 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 131975642 131975642 131975642 10.1007/s00394-017-1511-2 131975642 ppf: 2377 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Dietary total antioxidant capacity and incidence of chronic kidney disease in subjects with dysglycemia: Tehran Lipid and Glucose Study. aug: au: Asghari, Golaleh Yuzbashian, Emad Shahemi, Sahar Gaeini, Zahra Mirmiran, Parvin Azizi, Fereidoun affil: Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran sug: subj: Antioxidants Therapeutic Use Renal Insufficiency, Chronic Diet Therapy Blood Glucose Lipids Blood Hyperglycemia Human Incidence Iran Adult Middle Age Aged Aged, 80 and Over Dietary Supplementation Ascorbic Acid Therapeutic Use Vitamin E Therapeutic Use beta Carotene Therapeutic Use Questionnaires Miscellaneous Techniques Glomerular Filtration Rate Kidney Diseases Diet Therapy Odds Ratio Multivariate Analysis Logistic Regression Age Factors Sex Factors Smoking Physical Activity Body Mass Index Hypertension Energy Intake Confidence Intervals Renal Insufficiency, Chronic Risk Factors Hyperglycemia Diet Therapy Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over ab: Purpose: We aimed to investigate the association of dietary total antioxidant capacity (TAC) with incidence of CKD in subjects with dysglycemia.Methods: We followed-up 1179 subjects aged ≥30 years with dysglycemia from the Tehran Lipid and Glucose Study (TLGS) for 3 years, who were initially free of CKD. Dietary intakes of TAC, vitamin C, vitamin E, and β-carotene were assessed by a food-frequency questionnaire at the baseline. Dietary TAC was estimated using the oxygen radical absorbance capacity method. Estimated glomerular filtration rate (eGFR) was calculated, using the Modification of Diet in Renal Disease Study equation and CKD was defined as eGFR <60 mL/min/1.73 m2. Odds ratios (ORs) using multivariable logistic regression were reported for the association of incident CKD with dietary TAC.Results: A total of 197 (16.7%) cases of incident CKD were recorded after 3 years of follow-up. After adjustment for age, sex, smoking, physical activity, body mass index, hypertension, and total energy intake, the top tertile of dietary TAC compared to the bottom was associated with 39% [95% confidence interval (CI) = 0.40-0.93] lower risk of incident CKD (P for trend = 0.025). Furthermore, the highest tertile of vitamin C intake compared to the lowest risk of incident CKD was decreased (OR 0.60; 95% CI 0.38-0.93, P trend 0.023). Intakes of vitamin E and β-carotene were not significantly associated with incident CKD risk.Conclusion: Our findings suggest that diets high in TAC are associated with a lower risk of incident CKD among subjects with hyperglycemia after 3 years of follow-up. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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