5-HT1A parital agonism and 5-HT7 antagonism restore episodic memory in subchronic phencyclidine-treated mice: role of brain glutamate, dopamine, acetylcholine and GABA.

Rationale: The effect of atypical antipsychotic drugs (AAPDs), e.g., lurasidone, to improve cognitive impairment associated with schizophrenia (CIAS), has been suggested to be due, in part, to enhancing release of dopamine (DA), acetylcholine (ACh), and glutamate (Glu) in cortex and hippocampus.Resu...

Descripción completa

Detalles Bibliográficos
Publicado en:Psychopharmacology Vol. 235; no. 10; pp. 2795 - 2809
Autores principales: Huang, Mei, Kwon, Sunoh, Rajagopal, Lakshmi, He, Wenqi, Meltzer, Herbert Y.
Formato: Journal Article
Publicado: Springer Nature Oct2018
Acceso en línea:Ver este registro en EBSCOhost