Evaluation of liver parenchyma stiffness in patients with liver tumours: optimal strategy for shear wave elastography.
Objectives: To determine the methodology of non-invasive test for evaluation of liver stiffness (LS) with tumours using two-dimensional (2D) shear wave elastography (SWE).Methods: One hundred and twenty-seven patients with liver tumours underwent 2D-SWE before surgery to measure liver and spleen sti...
| Publicado en: | European Radiology Vol. 29; no. 3; pp. 1479 - 1489 |
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| Autores principales: | , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Mar2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=134415302&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 134415302 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Mar2019 vid: 29 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 134415302 134415302 NLM30105408 134415302 10.1007/s00330-018-5676-8 NLM30105408 134415302 ppf: 1479 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Evaluation of liver parenchyma stiffness in patients with liver tumours: optimal strategy for shear wave elastography. aug: au: Zheng, Wei Zhou, Zhong-guo Wong, Chong-hei Pei, Xiao-qing Zhuang, Shu-lian Li, Qing Chen, Min-Shan Li, An-hua Zhang, Fu-jun affil: Department of Ultrasound, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China; Collaborative Innovation Centre for Cancer Medicine, 510060, Guangzhou, Guangdong, People's Republic of China sug: subj: Ultrasonography Methods Liver Liver Neoplasms Pharmacokinetics Sensitivity and Specificity Liver Neoplasms Pathology Body Weights and Measures Prospective Studies Spleen Adult Middle Age Aged Spleen Pathology Liver Cirrhosis Female ROC Curve Liver Pathology Male Human Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Objectives: To determine the methodology of non-invasive test for evaluation of liver stiffness (LS) with tumours using two-dimensional (2D) shear wave elastography (SWE).Methods: One hundred and twenty-seven patients with liver tumours underwent 2D-SWE before surgery to measure liver and spleen stiffness (SS). Two-dimensional SWE values were obtained in the liver at 0-1 cm, 1-2 cm and >2 cm from the tumour edge (PLS-1, PLS-2 and RLS, respectively). The influence of tumour-associated factors was evaluated. The area under the receiver operating characteristic curve (AUC) for each value was analysed to diagnose cirrhosis.Results: PLS-1 was higher than PLS-2, which was even higher than RLS (p < 0.001). The AUCs of PLS-1, PLS-2, RLS and SS for diagnosing cirrhosis were 0.760, 0.833, 0.940 and 0.676, with the specificity of 75.7%, 67.6%, 90.3% and 77.4%, respectively. Tumour sizes, locations or types showed no apparent influence on 2D-SWE values except for RLS, which was higher in patients with primary hepatic carcinomas (p < 0.05).Conclusions: LS with tumours is best measured at >2 cm away from the tumour edge. SS measurement could be used as an alternative to LS measurement in the event of no available liver for detection.Key Points: • Tumour-associated factors impact background liver stiffness assessment. • Background liver stiffness is best measured at >2 cm from tumour edge. • Spleen stiffness can be an alternative to assess background liver stiffness. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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