Decreased Cortical Thickness in the Anterior Cingulate Cortex in Adults with Autism.
Autism spectrum disorder (ASD) is a developmental disorder underdiagnosed in adults. To date, no consistent evidence of alterations in brain structure has been reported in adults with ASD and few studies were conducted at that age. We analyzed structural magnetic resonance imaging data from 167 high...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 49; no. 4; pp. 1402 - 1410 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Apr2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=135779429&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 135779429 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Apr2019 vid: 49 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 135779429 135779429 135779429 10.1007/s10803-018-3807-3 135779429 ppf: 1402 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Decreased Cortical Thickness in the Anterior Cingulate Cortex in Adults with Autism. aug: au: Boisgontier, Jennifer Laidi, Charles Hotier, Sevan d'Albis, Marc-Antoine Houenou, Josselin Gaman, Alexandru Scheid, Isabelle Leboyer, Marion Toledano, Elie Ly-Le Moal, Myriam Delorme, Richard de Pierrefeu, Amicie Duchesnay, Edouard Petit, Julie Bolognani, Federico Czech, Christian Bouquet, Céline Holiga, Štefan Dukart, Juergen Amestoy, Anouck affil: Institut National de la Santé et de la Recherche Médicale (INSERM), U955, Institut Mondor de Recherche Biomédicale, Psychiatrie Translationnelle (Créteil, France), 51 Avenue du Maréchal de Lattre de Tassigny, 94010, Créteil, France sug: subj: Limbic System Pathology Autism Spectrum Disorder Diagnosis Magnetic Resonance Imaging Methods Human Adult Persons with Disabilities Adult: 19-44 years ab: Autism spectrum disorder (ASD) is a developmental disorder underdiagnosed in adults. To date, no consistent evidence of alterations in brain structure has been reported in adults with ASD and few studies were conducted at that age. We analyzed structural magnetic resonance imaging data from 167 high functioning adults with ASD and 195 controls. We ran our analyses on a discovery (n = 301) and a replication sample (n = 61). The right caudal anterior cingulate cortical thickness was significantly thinner in adults with ASD compared to controls in both the discovery and the replication sample. Our work underlines the relevance of studying the brain anatomy of an adult ASD population. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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