Post-surgical Pyoderma Gangrenosum: A Retrospective Analysis of four Clinical Cases.
Background Pyoderma gangrenosum (PG) is a rare neutrophilic disease that is characterised by the pathergy phenomenon, as it worsens with trauma. Post-surgical PG (PSPG) occurs in surgical incisions and is typically first misdiagnosed as a surgical site infection. The diagnostic delay in PSPG is ofte...
| Publicado en: | EWMA Journal Vol. 20; no. 1; pp. 37 - 41 |
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| Autor principal: | |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Cambridge Publishing
May2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | Background Pyoderma gangrenosum (PG) is a rare neutrophilic disease that is characterised by the pathergy phenomenon, as it worsens with trauma. Post-surgical PG (PSPG) occurs in surgical incisions and is typically first misdiagnosed as a surgical site infection. The diagnostic delay in PSPG is often considerable. Hypothesis/Aim The aim of this study was to analyse patient records with PSPG that were diagnosed in our Department of Dermatology; with special focus on the diagnostic delay and treatment outcomes. Methods The records of four patient cases that were diagnosed with PSPG in our Department of Dermatology from 2017 to 2018 were analysed retrospectively. Results The average delay in diagnosis was 5 months, and the diagnosis could not rely on histological findings. Prednisolone treatment led to complete wound healing in three cases. In one case, switching from prednisolone to cyclosporine eventually healed the wound. Conclusions The diagnostic delay was considerable, and prednisolone and cyclosporine were considered as effective treatments. |
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