| Sumario: | Background: Pulse oximetry is considered as the most valuable non-invasive method for continuous oxygen saturation (SpO2) monitoring in patients with hypoxemia risk. Aim: The aim of this study to determine whether nail polish affected peripheral capillary hemoglobin oxygen saturation measurements in healthy individuals Methodology: This is a semi-experimental study.. This research was conducted with the 80 female who 18 age and above and not having any health problem, not having any communication problem, non-smoker, agreed to participate in study at a Nursing Department from January 2015 to June 2015 were included. The right hand of the participants was selected as the hand to receive nail polish for the experiment, while the left hand was used as a control without nail polish. A portable pulse oximeter was used for oxygen saturation measurement. Results; There was statistical significant difference between SpO2 measurements performed on the right and left thumbs (color pearl, p=.000). Similarly, statistically significant differences were found between measurements of right and left hand index finger (color red, p=.000), middle finger (color blue, p=.000), ring finger (color brown, p=.000) and small finger (color green, p=.000). Conclusion: As a result, all the nail polish colors caused a reduction in the measurement of SpO2. Nurses may be recommended to remove nail polish of the patients before measuring oxygen saturation on the finger
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