Eupatilin: a natural pharmacologically active flavone compound with its wide range applications.

Eupatilin (5,7-dihydroxy-3′,4′,6-trimethoxyflavone) is a pharmacologically active flavone which has been isolated from a variety of medicinal plants. Eupatilin is known to possess various pharmacological properties such as anti-cancer, anti-oxidant, and anti-inflammatory. It is speculated that eupat...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Asian Natural Products Research Vol. 22; no. 1; pp. 1 - 17
Autores principales: Nageen, Bushra, Sarfraz, Iqra, Rasul, Azhar, Hussain, Ghulam, Rukhsar, Fariha, Irshad, Somia, Riaz, Ammara, Selamoglu, Zeliha, Ali, Muhammad
Formato: pictorial review tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jan2020
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Eupatilin (5,7-dihydroxy-3′,4′,6-trimethoxyflavone) is a pharmacologically active flavone which has been isolated from a variety of medicinal plants. Eupatilin is known to possess various pharmacological properties such as anti-cancer, anti-oxidant, and anti-inflammatory. It is speculated that eupatilin could be subjected to structural optimization for the synthesis of derivative analogs to reinforce its efficacy, to minimize toxicity, and to optimize absorption profiles, which will ultimately lead towards potent drug candidates. Although, reported data acclaim multiple pharmacological activities of eupatilin but further experimentations on its molecular mechanism of action are yet mandatory to elucidate full spectrum of its pharmacological activities.