Eupatilin: a natural pharmacologically active flavone compound with its wide range applications.

Eupatilin (5,7-dihydroxy-3′,4′,6-trimethoxyflavone) is a pharmacologically active flavone which has been isolated from a variety of medicinal plants. Eupatilin is known to possess various pharmacological properties such as anti-cancer, anti-oxidant, and anti-inflammatory. It is speculated that eupat...

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Published in:Journal of Asian Natural Products Research Vol. 22; no. 1; pp. 1 - 17
Main Authors: Nageen, Bushra, Sarfraz, Iqra, Rasul, Azhar, Hussain, Ghulam, Rukhsar, Fariha, Irshad, Somia, Riaz, Ammara, Selamoglu, Zeliha, Ali, Muhammad
Format: pictorial review tables/charts Journal Article
Published: Taylor & Francis Ltd Jan2020
Online Access:View this record in EBSCOhost
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      jtl: Journal of Asian Natural Products Research
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      dt: Jan2020
      vid: 22
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/10286020.2018.1492565
        141083306
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        atl: Eupatilin: a natural pharmacologically active flavone compound with its wide range applications.
      aug:
        au:
          Nageen, Bushra
          Sarfraz, Iqra
          Rasul, Azhar
          Hussain, Ghulam
          Rukhsar, Fariha
          Irshad, Somia
          Riaz, Ammara
          Selamoglu, Zeliha
          Ali, Muhammad
        affil: Faculty of Life Sciences, Department of Zoology, Government College University Faisalabad, Faisalabad, 38000, Pakistan
      sug:
        subj:
          Plants, Medicinal
          Flavones Pharmacodynamics
          Flavones Pharmacokinetics
          Antineoplastic Agents
          Antiinflammatory Agents
          Antioxidants
          Flavones Analogs and Derivatives
          Biological Products
          Molecular Structure
          Apoptosis Drug Effects
          Cell Cycle Drug Effects
          Signal Transduction Drug Effects
          Neuroprotective Agents
          Flavones Therapeutic Use
          Cardiotonic Agents
          Histamine H1 Antagonists
      ab: Eupatilin (5,7-dihydroxy-3′,4′,6-trimethoxyflavone) is a pharmacologically active flavone which has been isolated from a variety of medicinal plants. Eupatilin is known to possess various pharmacological properties such as anti-cancer, anti-oxidant, and anti-inflammatory. It is speculated that eupatilin could be subjected to structural optimization for the synthesis of derivative analogs to reinforce its efficacy, to minimize toxicity, and to optimize absorption profiles, which will ultimately lead towards potent drug candidates. Although, reported data acclaim multiple pharmacological activities of eupatilin but further experimentations on its molecular mechanism of action are yet mandatory to elucidate full spectrum of its pharmacological activities.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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