ABCC2 c.-24 C>T single-nucleotide polymorphism was associated with the pharmacokinetic variability of deferasirox in Chinese subjects.

Purpose: Our aim was to evaluate the influence of genetic polymorphisms involved in the metabolism and transportation of deferasirox on deferasirox pharmacokinetics in the Chinese population. Methods: Thirty-eight healthy Chinese subjects were administered with a single dose of 20 mg kg−1 deferasiro...

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Bibliographic Details

Published in:	European Journal of Clinical Pharmacology Vol. 76; no. 1; pp. 51 - 60
Main Authors:	Cao, Kangna, Ren, Guanghui, Lu, Chengcan, Wang, Yao, Tan, Yanan, Zhou, Jing, Zhang, Yongjie, Lu, Yang, Li, Ning, Chen, Xijing, Zhao, Di
Format:	research tables/charts Journal Article
Published:	Springer Nature Jan2020
Online Access:	View this record in EBSCOhost