ABCC2 c.-24 C>T single-nucleotide polymorphism was associated with the pharmacokinetic variability of deferasirox in Chinese subjects.
Purpose: Our aim was to evaluate the influence of genetic polymorphisms involved in the metabolism and transportation of deferasirox on deferasirox pharmacokinetics in the Chinese population. Methods: Thirty-eight healthy Chinese subjects were administered with a single dose of 20 mg kg−1 deferasiro...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 76; no. 1; pp. 51 - 60 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jan2020
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| Acceso en línea: | Ver este registro en EBSCOhost |