Initial dose optimization of tacrolimus for children with systemic lupus erythematosus based on the CYP3A5 polymorphism and coadministration with Wuzhi capsule.

What is known and objectives: Tacrolimus, an immunosuppressant, has been used to treat paediatric systemic lupus erythematosus, but the optimal initial regimen is not clear. The purpose of this study was to explore the optimal initial dose of tacrolimus for children with systemic lupus erythematosus...

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Detalles Bibliográficos
Publicado en:Journal of Clinical Pharmacy & Therapeutics Vol. 45; no. 2; pp. 309 - 318
Autores principales: Chen, Xiao, Wang, Dongdong, Xu, Hong, Li, Zhiping
Formato: equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell Apr2020
Acceso en línea:Ver este registro en EBSCOhost