MRI-biochemical follow up measurements of lumbar intervertebral disc in patients with leg length discrepancy: Is it possible to alter cartilage damage with conservative therapy?
Objective: Effect of conservative therapy on intervertebral discs (IVD) in patients with leg-length-discrepancy (LLD). M&M: Seventy lumbar IVDs of 14 participants (five with LLD 10-20 mm) were examined using a 3T-MRI-scanner. Morphological (Pfirrmann) and molecular (glycosaminoglycan-chemical-exchan...
| Publicado en: | Journal of Orthopaedics Vol. 16; no. 6; pp. 473 - 478 |
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| Autores principales: | , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Professor PK Surendran Memorial Education Foundation
Nov/Dec2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=142874313&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 142874313 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 25899082 1CUL jtl: Journal of Orthopaedics issn: 25899082 maglogo: N pubinfo: dt: Nov/Dec2019 vid: 16 iid: 6 pid: 24594 pub: Professor PK Surendran Memorial Education Foundation artinfo: ui: 142874313 142874313 142874313 10.1016/j.jor.2019.06.006 142874313 ppf: 473 ppct: 5 formats: fmt: @attributes: type: P tig: atl: MRI-biochemical follow up measurements of lumbar intervertebral disc in patients with leg length discrepancy: Is it possible to alter cartilage damage with conservative therapy? aug: au: Frenken, Miriam Latz, David Schiffner, Erik Quante, Wolfgang Alois Knautz, Maxime Abrar, Daniel Benjamin Schaarschmidt, Benedikt Schleich, Christoph affil: Department for Diagnostic and Interventional Radiology and University Hospital Dusseldorf, Heinrich-Heine-University, Dusseldorf, Germany sug: subj: Leg Length Inequality Therapy Magnetic Resonance Imaging Methods Glycosaminoglycans Metabolism Molecular Imaging Methods Lumbar Vertebrae Pathology Intervertebral Disk Pathology Spinal Diseases Risk Factors Leg Length Inequality Complications Risk Assessment Human Physical Therapy Orthopedic Footwear Prospective Studies ab: Objective: Effect of conservative therapy on intervertebral discs (IVD) in patients with leg-length-discrepancy (LLD). M&M: Seventy lumbar IVDs of 14 participants (five with LLD 10-20 mm) were examined using a 3T-MRI-scanner. Morphological (Pfirrmann) and molecular (glycosaminoglycan-chemical-exchange-saturation-transfer, gagCEST) grading was assessed before and after a four-month therapy (physiotherapy and shoe inlays). Results: Significantly lower GAG values in patients with LLD were found (L5/S1, p=0.02). After therapy, a trend towards higher gagCEST values in patients with LLD was observed (2.48 ± 1.77% vs. 1.79 ± 0.79%; p > 0.05). Conclusion: LLD represents a risk factor for molecular alterations of lumbar IVDs. Only minor effects of conservative therapy on these alterations could be found. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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