Light-Adapted Electroretinogram Differences in Autism Spectrum Disorder.
Light-adapted (LA) electroretinograms (ERGs) from 90 individuals with autism spectrum disorder (ASD), mean age (13.0 ± 4.2), were compared to 87 control subjects, mean age (13.8 ± 4.8). LA-ERGs were produced by a random series of nine different Troland based, full-field flash strengths and the ISCEV...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 50; no. 8; pp. 2874 - 2886 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | pictorial research tables/charts tracings Journal Article |
| Publicado: |
Springer Nature
Aug2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=144696590&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 144696590 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Aug2020 vid: 50 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 144696590 144152041 144696590 144696590 10.1007/s10803-020-04396-5 144696590 ppf: 2874 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Light-Adapted Electroretinogram Differences in Autism Spectrum Disorder. aug: au: Constable, Paul A. Ritvo, Edward R. Ritvo, Ariella R. Lee, Irene O. McNair, Morgan L. Stahl, Dylan Sowden, Jane Quinn, Stephen Skuse, David H. Thompson, Dorothy A. McPartland, James C. affil: Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, GPO Box 2100, 5001, Adelaide, SA, Australia sug: subj: Autism Spectrum Disorder Physiopathology Electroretinography Methods Retina Physiopathology Children with Disabilities Human Child Adolescence Electrophysiology Neurophysiology Child: 6-12 years Adolescent: 13-18 years ab: Light-adapted (LA) electroretinograms (ERGs) from 90 individuals with autism spectrum disorder (ASD), mean age (13.0 ± 4.2), were compared to 87 control subjects, mean age (13.8 ± 4.8). LA-ERGs were produced by a random series of nine different Troland based, full-field flash strengths and the ISCEV standard flash at 2/s on a 30 cd m−2 white background. A random effects mixed model analysis showed the ASD group had smaller b- and a-wave amplitudes at high flash strengths (p <.001) and slower b-wave peak times (p <.001). Photopic hill models showed the peaks of the component Gaussian (p =.035) and logistic functions (p =.014) differed significantly between groups. Retinal neurophysiology assessed by LA-ERG provides insight into neural development in ASD. pubtype: Academic Journal doctype: pictorial research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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