Chronic Peripheral Ghrelin Injection Exerts Antifibrotic Effects by Increasing Growth Differentiation Factor 15 in Rat Hearts With Myocardial Fibrosis Induced by Isoproterenol.
This study aimed to investigate the anti-fibrotic effects of ghrelin in isoproterenol (ISO)-induced myocardial fibrosis and the underlying mechanism. Sprague-Dawley rats were randomized to control, ISO, and ISO + ghrelin groups. ISO (2 mg/kg per day, subcutaneous) or vehicle was administered once da...
| Published in: | Physiological Research Vol. 69; no. 3; pp. 439 - 451 |
|---|---|
| Main Authors: | , , , , |
| Format: | Journal Article |
| Published: |
Institute of Physiology, Academy of Sciences of the Czech Republic
Jun2020
|
| Online Access: | View this record in EBSCOhost |