Detection of Copy Number Alterations by Shallow Whole-Genome Sequencing of Formalin-Fixed, Paraffin-Embedded Tumor Tissue.

Context.-- In routine clinical practice, tumor tissue is stored in formalin-fixed, paraffin-embedded blocks. However, the use of formalin-fixed, paraffin-embedded tissue for genome analysis is challenged by poorer DNA quality and quantity. Although several studies have reported genome-wide massive p...

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Publicado en:Archives of Pathology & Laboratory Medicine Vol. 144; no. 8; pp. 974 - 982
Autores principales: Van der Linden, Malaïka, Raman, Lennart, Vander Trappen, Ansel, Dheedene, Annelies, De Smet, Matthias, Sante, Tom, Creytens, David, Lievens, Yolande, Menten, Björn, Van Dorpe, Jo, Van Roy, Nadine
Formato: Journal Article
Publicado: College of American Pathologists Aug2020
Acceso en línea:Ver este registro en EBSCOhost