FTY720 reactivates cryptococcal granulomas in mice through S1P receptor 3 on macrophages.

FTY720 is a treatment for relapsing remitting multiple sclerosis (MS). It is an analog of sphingosine-1-phosphate (S1P) and targets S1P receptors 1, 3, 4, and 5. Recent reports indicate an association between long-term exposure to FTY720 and cases of cryptococcal infection. Here, we studied the effe...

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Publicado en:	Journal of Clinical Investigation Vol. 130; no. 9; pp. 4546 - 4561
Autores principales:	Bryan, Arielle M., You, Jeehyun Karen, McQuiston, Travis, Lazzarini, Cristina, Zhijuan Qiu, Sheridan, Brian, Nuesslein-Hildesheim, Barbara, Del Poeta, Maurizio, Qiu, Zhijuan, Sheridan, Brian S
Formato:	research Journal Article
Publicado:	American Society for Clinical Investigation Sep2020
Acceso en línea:	Ver este registro en EBSCOhost