Patient selection for a developmental therapeutics program using whole genome and Transcriptome analysis.

Summary: Introduction Given the high level of uncertainty surrounding the outcomes of early phase clinical trials, whole genome and transcriptome analysis (WGTA) can be used to optimize patient selection and study assignment. In this retrospective analysis, we reviewed the impact of this approach on...

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Publicado en:Investigational New Drugs Vol. 38; no. 5; pp. 1601 - 1605
Autores principales: Lavoie, Jean-Michel, Mitchell, Teresa, Lee, Sung-Eun, Deol, Balvir, Chia, Stephen K., Gelmon, Karen A., Kollmannsberger, Christian K., Tinker, Anna V., Jones, Steven J. M., Marra, Marco, Laskin, Janessa, Renouf, Daniel J.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Oct2020
Acceso en línea:Ver este registro en EBSCOhost