Patient selection for a developmental therapeutics program using whole genome and Transcriptome analysis.

Summary: Introduction Given the high level of uncertainty surrounding the outcomes of early phase clinical trials, whole genome and transcriptome analysis (WGTA) can be used to optimize patient selection and study assignment. In this retrospective analysis, we reviewed the impact of this approach on...

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Bibliographic Details
Published in:Investigational New Drugs Vol. 38; no. 5; pp. 1601 - 1605
Main Authors: Lavoie, Jean-Michel, Mitchell, Teresa, Lee, Sung-Eun, Deol, Balvir, Chia, Stephen K., Gelmon, Karen A., Kollmannsberger, Christian K., Tinker, Anna V., Jones, Steven J. M., Marra, Marco, Laskin, Janessa, Renouf, Daniel J.
Format: research tables/charts Journal Article
Published: Springer Nature Oct2020
Online Access:View this record in EBSCOhost