A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cancer.

Background: The role of nuclear receptors in both the aetiology and treatment of breast cancer is exemplified by the use of the oestrogen receptor (ER) as a prognostic marker and treatment target. Treatments targeting the oestrogen signalling pathway are initially highly effective for most patients....

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Detalles Bibliográficos
Publicado en:Breast Cancer Research Vol. 22; no. 1
Autores principales: Doan, Tram B., Cheung, Vanessa, Clyne, Colin D., Hilton, Heidi N., Eriksson, Natalie, Young, Morag J., Funder, John W., Muscat, George E. O., Fuller, Peter J., Clarke, Christine L., Graham, J. Dinny
Formato: research Journal Article
Publicado: BioMed Central 11/4/2020
Acceso en línea:Ver este registro en EBSCOhost