A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cancer.

Background: The role of nuclear receptors in both the aetiology and treatment of breast cancer is exemplified by the use of the oestrogen receptor (ER) as a prognostic marker and treatment target. Treatments targeting the oestrogen signalling pathway are initially highly effective for most patients....

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Bibliographic Details

Published in:	Breast Cancer Research Vol. 22; no. 1
Main Authors:	Doan, Tram B., Cheung, Vanessa, Clyne, Colin D., Hilton, Heidi N., Eriksson, Natalie, Young, Morag J., Funder, John W., Muscat, George E. O., Fuller, Peter J., Clarke, Christine L., Graham, J. Dinny
Format:	research Journal Article
Published:	BioMed Central 11/4/2020
Online Access:	View this record in EBSCOhost