Detection of Pathogenic Isoforms of IKZF1 in Leukemic Cell Lines and Acute Lymphoblastic Leukemia Samples: Identification of a Novel Truncated IKZF1 Transcript in SUP-B15.

Simple Summary: Abnormal RNA splicing plays a fundamental role in leukemogenesis in acute lymphoblastic leukemia (ALL). Many cases of high-risk B-cell ALL cases, including BCR-ABL1+ and BCR-ABL1-like ALL, share a common molecular mechanism of aberrant fusion transcripts involving tyrosine kinase gen...

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Bibliographic Details

Published in:	Cancers Vol. 12; no. 11; pp. 3161 - 3162
Main Authors:	Zhao, Weiqiang, Li, Ying, Yao, Chenjiao, Zhang, Guojuan, Zhao, Kevin Y., Chen, Wei, Ru, Peng, Pan, Xiaokang, Tu, Huolin, Jones, Daniel
Format:	pictorial research tables/charts Journal Article
Published:	MDPI Nov2020
Online Access:	View this record in EBSCOhost