Effect of Mild Physiologic Hyperglycemia on Insulin Secretion, Insulin Clearance, and Insulin Sensitivity in Healthy Glucose-Tolerant Subjects.

The aim of the current study was to evaluate the effect of sustained physiologic increase of ∼50 mg/dL in plasma glucose concentration on insulin secretion in normal glucose-tolerant (NGT) subjects. Twelve NGT subjects without family history of type 2 diabetes mellitus (T2DM; FH-) and 8 NGT with fam...

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Bibliographic Details

Published in:	Diabetes Vol. 70; no. 1; pp. 204 - 214
Main Authors:	Merovci, Aurora, Tripathy, Devjit, Chen, Xi, Valdez, Ivan, Abdul-Ghani, Muhammad, Solis-Herrera, Carolina, Gastaldelli, Amalia, DeFronzo, Ralph A.
Format:	research Journal Article
Published:	American Diabetes Association Jan2021
Online Access:	View this record in EBSCOhost