Cognitive-Motor Interference Heightens the Prefrontal Cortical Activation and Deteriorates the Task Performance in Children With Hemiplegic Cerebral Palsy.

To compare the prefrontal cortex (PFC) activation and task performance during single- and dual-task conditions between typically developing (TD) children and children with hemiplegic cerebral palsy (HCP). A prospective, comparative design. Research laboratory. Participants (N=21) included 12 TD chil...

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Publicado en:Archives of Physical Medicine & Rehabilitation Vol. 102; no. 2; pp. 225 - 233
Autores principales: Surkar, Swati M., Hoffman, Rashelle M., Harbourne, Regina, Kurz, Max J.
Formato: research tables/charts Journal Article
Publicado: W B Saunders Feb2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2021
      vid: 102
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      pub: W B Saunders
      place: Philadelphia, Pennsylvania
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        148283432
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        10.1016/j.apmr.2020.08.014
        148283432
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        atl: Cognitive-Motor Interference Heightens the Prefrontal Cortical Activation and Deteriorates the Task Performance in Children With Hemiplegic Cerebral Palsy.
      aug:
        au:
          Surkar, Swati M.
          Hoffman, Rashelle M.
          Harbourne, Regina
          Kurz, Max J.
        affil: Department of Physical Therapy, East Carolina University, Greenville, North Carolina
      sug:
        subj:
          Psychomotor Performance
          Frontal Lobe Physiology
          Task Performance and Analysis
          Cerebral Palsy In Infancy and Childhood
          Human
          Prospective Studies
          Comparative Studies
          Female
          Male
          Child, Preschool
          Child
          Cognition
          Academic Medical Centers
          Spectroscopy, Near-Infrared
          Data Analysis Software
          Analysis of Variance
          Funding Source
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Female
          Male
      ab: To compare the prefrontal cortex (PFC) activation and task performance during single- and dual-task conditions between typically developing (TD) children and children with hemiplegic cerebral palsy (HCP). A prospective, comparative design. Research laboratory. Participants (N=21) included 12 TD children (age, 6.0±1.1y) and 9 children with HCP (age, 7.2±3.1). Not applicable. PFC activation was assessed by measuring the concentration of oxygenated hemoglobin while the children performed a shape-matching task with their more affected arm while sitting on a stable (single task) vs dynamic surface (dual task). The task performance was assessed with the total number of shapes matched, dual-task cost, and reaction time (RT). For both conditions, the children with HCP exhibited greater PFC activation, matched a fewer shapes, and had slower RT than the TD children. These differences were accentuated during the dual-task condition and the dual-task cost was greater. An increase in the PFC activation during the dual-task condition was tightly correlated with a higher dual-task cost in children with HCP (r =0.77, P =.01). Children with HCP appear to have a heightened amount of PFC activity while performing a dual task. The greater cortical activity may be a result of the finite attentional resources that are shared between both the motor as well as cognitive demands of the task. The cognitive-motor interference is likely exacerbated in children with HCP because of the structural and functional brain changes as a result of an insult to the developing brain. • This is the first study that assessed the neural substrate of cognitive-motor interference during goal-directed upper extremity dual-task in children with hemiplegic cerebral palsy (HCP). • Children with HCP have greater activation within the prefrontal cortex while performing goal-directed dual task with the affected upper extremity, which indicates a greater degree of burden imposed on the prefrontal cortex for simultaneously processing the cognitive-motor demands of dual task. • Cognitive-motor interference deteriorates task performance, such as resulting increase in reaction time and reduced number of shapes matched in children with HCP.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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